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Cryo-EM structures of intact V-ATPase from bovine brain
The vacuolar-type H(+)-ATPases (V-ATPase) hydrolyze ATP to pump protons across the plasma or intracellular membrane, secreting acids to the lumen or acidifying intracellular compartments. It has been implicated in tumor metastasis, renal tubular acidosis, and osteoporosis. Here, we report two cryo-E...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414150/ https://www.ncbi.nlm.nih.gov/pubmed/32764564 http://dx.doi.org/10.1038/s41467-020-17762-9 |