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Distribution and clinical impact of apolipoprotein E4 in subjective memory impairment and early mild cognitive impairment
The apolipoprotein E (APOE) e4 allele is the most common genetic variant associated with Alzheimer’s disease (AD). We sought to investigate the distribution of APOE genotypes across the full clinical AD spectrum including AD, late-stage amnestic mild cognitive impairment (L-aMCI), early-stage aMCI (...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414226/ https://www.ncbi.nlm.nih.gov/pubmed/32770103 http://dx.doi.org/10.1038/s41598-020-69603-w |