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Distribution and clinical impact of apolipoprotein E4 in subjective memory impairment and early mild cognitive impairment

The apolipoprotein E (APOE) e4 allele is the most common genetic variant associated with Alzheimer’s disease (AD). We sought to investigate the distribution of APOE genotypes across the full clinical AD spectrum including AD, late-stage amnestic mild cognitive impairment (L-aMCI), early-stage aMCI (...

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Detalles Bibliográficos
Autores principales: Cho, Hanna, Kim, Young-Eun, Chae, Wonjeong, Kim, Ko Woon, Kim, Jong-Won, Kim, Hee Jin, Na, Duk L., Ki, Chang-Seok, Seo, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414226/
https://www.ncbi.nlm.nih.gov/pubmed/32770103
http://dx.doi.org/10.1038/s41598-020-69603-w