NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB(p65) and actin cytoskeleton regulatory pathways

Glioblastoma (GBM) is the most malignant brain tumor characterized by intrinsic or acquired resistance to chemotherapy. GBM tumors show nuclear factor-κB (NF-κB) activity that has been associated with tumor formation, growth, and increased resistance to therapy. We investigated the effect of NF-κB i...

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Detalles Bibliográficos
Autores principales: Avci, Naze G., Ebrahimzadeh-Pustchi, Sadaf, Akay, Yasemin M., Esquenazi, Yoshua, Tandon, Nitin, Zhu, Jay-Jiguang, Akay, Metin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414229/
https://www.ncbi.nlm.nih.gov/pubmed/32770097
http://dx.doi.org/10.1038/s41598-020-70392-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414229/
https://www.ncbi.nlm.nih.gov/pubmed/32770097
http://dx.doi.org/10.1038/s41598-020-70392-5

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