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Crystallographic evidence of Watson–Crick connectivity in the base pair of anionic adenine with thymine

Utilizing an ionic liquid strategy, we report crystal structures of salts of free anionic nucleobases and base pairs previously studied only computationally and in the gas phase. Reaction of tetrabutylammonium ([N(4444)](+)) or tetrabutylphosphonium ([P(4444)](+)) hydroxide with adenine (HAd) and th...

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Detalles Bibliográficos
Autores principales: Mishra, Manish Kumar, Kelley, Steven P., Smetana, Volodymyr, Dixon, David A., McNeill, Ashley S., Mudring, Anja-Verena, Rogers, Robin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414232/
https://www.ncbi.nlm.nih.gov/pubmed/32680959
http://dx.doi.org/10.1073/pnas.2008379117