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2’-Fluoro-2’-deoxycytidine inhibits murine norovirus replication and synergizes MPA, ribavirin and T705

Noroviruses are the main causative agents of acute viral gastroenteritis worldwide. However, no vaccine or specific antiviral treatment is available, imposing a heavy global health burden. The nucleoside analogue 2’-fluoro-2’-deoxycytidine (2’-FdC) has been reported to have broad antiviral activity....

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Detalles Bibliográficos
Autores principales: Yu, Peifa, Wang, Yining, Li, Yunlong, Li, Yang, Miao, Zhijiang, Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414258/
https://www.ncbi.nlm.nih.gov/pubmed/32770483
http://dx.doi.org/10.1007/s00705-020-04759-4