Genotoxic Effects of Etoposide, Bleomycin, and Ethyl Methanesulfonate on Cultured CHO Cells: Analysis by GC-MS/MS and Comet Assay

To evaluate methods for analysis of genotoxic effects on mammalian cell lines, we tested the effect of three common genotoxic agents on Chinese hamster ovary (CHO) cells by single-cell gel electrophoresis (comet assay) and gas chromatography-tandem mass spectrometry (GC-MS/MS). Suspension-grown CHO...

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Detalles Bibliográficos
Autores principales: Atha, Donald H., Coskun, Erdem, Erdem, Onur, Tona, Alessandro, Reipa, Vytas, Nelson, Bryant C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414336/
https://www.ncbi.nlm.nih.gov/pubmed/32802493
http://dx.doi.org/10.1155/2020/8810105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414336/
https://www.ncbi.nlm.nih.gov/pubmed/32802493
http://dx.doi.org/10.1155/2020/8810105

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