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Biological properties of influenza A virus mutants with amino acid substitutions in the HA2 glycoprotein of the HA1/HA2 interaction region

Influenza A viruses (IAVs) enter into cells by receptor-dependent endocytosis. Subsequently, conformational changes of haemagglutinin are triggered by low environmental pH and the N terminus of HA2 glycoprotein (gp) is inserted into the endosomal membrane, resulting in fusion pore formation and geno...

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Detalles Bibliográficos
Autores principales: Jakubcová, L., Vozárová, M., Hollý, J., Tomčíková, K., Fogelová, M., Polčicová, K., Kostolanský, F., Fodor, E., Varečková, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414431/
https://www.ncbi.nlm.nih.gov/pubmed/31329089
http://dx.doi.org/10.1099/jgv.0.001305