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N-glycosylation of infectious bronchitis virus M41 spike determines receptor specificity

Infection of chicken coronavirus infectious bronchitis virus (IBV) is initiated by binding of the viral heavily N-glycosylated attachment protein spike to the alpha-2,3-linked sialic acid receptor Neu5Ac. Previously, we have shown that N-glycosylation of recombinantly expressed receptor binding doma...

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Detalles Bibliográficos
Autores principales: Bouwman, K. M., Habraeken, N., Laconi, A., Berends, A. J., Groenewoud, L., Alders, M., Kemp, V., Verheije, M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414442/
https://www.ncbi.nlm.nih.gov/pubmed/32213247
http://dx.doi.org/10.1099/jgv.0.001408