Leaky scanning translation generates a second A49 protein that contributes to vaccinia virus virulence

Vaccinia virus (VACV) strain Western Reserve gene A49L encodes a small intracellular protein with a Bcl-2 fold that is expressed early during infection and has multiple functions. A49 co-precipitates with the E3 ubiquitin ligase β-TrCP and thereby prevents ubiquitylation and proteasomal degradation...

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Detalles Bibliográficos
Autores principales: Neidel, Sarah, Torres, Alice A., Ren, Hongwei, Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414448/
https://www.ncbi.nlm.nih.gov/pubmed/32100702
http://dx.doi.org/10.1099/jgv.0.001386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414448/
https://www.ncbi.nlm.nih.gov/pubmed/32100702
http://dx.doi.org/10.1099/jgv.0.001386

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