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Passage of influenza A/H3N2 viruses in human airway cells removes artefactual variants associated with neuraminidase-mediated binding

Serological assays with modern influenza A/H3N2 viruses have become problematic due to the progressive reduction in the ability of viruses of this subtype to bind and agglutinate red blood cells (RBCs). This is due to reduced ability of the viral haemagglutinin (HA) glycoprotein to bind to the siali...

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Detalles Bibliográficos
Autores principales: Brown, Jonathan C., Barclay, Wendy S., Galiano, Monica, Harvey, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414449/
https://www.ncbi.nlm.nih.gov/pubmed/31702542
http://dx.doi.org/10.1099/jgv.0.001348