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KAP1 silencing relieves OxLDL-induced vascular endothelial dysfunction by down-regulating LOX-1

KRAB domain-associated protein 1 (KAP1) is highly expressed in atherosclerotic plaques. Here, we studied the role of KAP1 in atherosclerosis development using a cell model of endothelial dysfunction induced by oxidative low-density lipoprotein (OxLDL). The phosphorylation and protein levels of KAP1...

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Detalles Bibliográficos
Autores principales: Yan, Tianqing, Liang, Chang, Fan, Haidi, Zhou, Wei, Huang, Linyan, Qi, Suhua, Wang, Wan, Ma, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414520/
https://www.ncbi.nlm.nih.gov/pubmed/32725144
http://dx.doi.org/10.1042/BSR20200821