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Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway

BACKGROUND: To clarify the role of apolipoprotein D (Apod) in alleviating glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells (MSCs) via the PI3K/Akt pathway, thus influencing the progression of osteoporosis (OP). METHODS: Osteogenesis in MSCs was induced by dexamet...

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Detalles Bibliográficos
Autores principales: Yu, Rong-Hua, Zhang, Xiang-yang, Xu, Wei, Li, Zhi-kun, Zhu, Xiao-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414572/
https://www.ncbi.nlm.nih.gov/pubmed/32771037
http://dx.doi.org/10.1186/s13018-020-01824-1