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PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins

BACKGROUND: The PIM family kinases promote cancer cell survival and motility as well as metastatic growth in various types of cancer. We have previously identified several PIM substrates, which support cancer cell migration and invasiveness. However, none of them are known to regulate cellular movem...

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Detalles Bibliográficos
Autores principales: Santio, Niina M., Vainio, Veera, Hoikkala, Tuuli, Mung, Kwan Long, Lång, Mirka, Vahakoski, Riitta, Zdrojewska, Justyna, Coffey, Eleanor T., Kremneva, Elena, Rainio, Eeva-Marja, Koskinen, Päivi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414696/
https://www.ncbi.nlm.nih.gov/pubmed/32771000
http://dx.doi.org/10.1186/s12964-020-00618-6