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Microglia activation visualization via fluorescence lifetime imaging microscopy of intrinsically fluorescent metabolic cofactors

Significance: A major obstacle to studying resident microglia has been their similarity to infiltrating immune cell types and the lack of unique protein markers for identifying the functional state. Given the role of microglia in all neural diseases and insults, accurate tools for detecting their fu...

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Detalles Bibliográficos
Autores principales: Sagar, Md. Abdul K., Ouellette, Jonathan N., Cheng, Kevin P., Williams, Justin C., Watters, Jyoti J., Eliceiri, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414793/
https://www.ncbi.nlm.nih.gov/pubmed/32821772
http://dx.doi.org/10.1117/1.NPh.7.3.035003