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Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates

The rise of antibiotic resistance in many bacterial pathogens has been driven by the spread of a few successful strains, suggesting that some bacteria are genetically pre-disposed to evolving resistance. Here, we test this hypothesis by challenging a diverse set of 222 isolates of Staphylococcus aur...

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Detalles Bibliográficos
Autores principales: Papkou, Andrei, Hedge, Jessica, Kapel, Natalia, Young, Bernadette, MacLean, R. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414891/
https://www.ncbi.nlm.nih.gov/pubmed/32769975
http://dx.doi.org/10.1038/s41467-020-17735-y