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A single unified model for fitting simple to complex receptor response data
The fitting of complex receptor-response data where fractional response and occupancy do not match is challenging. They encompass important cases including (a) the presence of “receptor reserve” and/or partial agonism, (b) multiple responses assessed at different vantage points along a pathway, (c)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414914/ https://www.ncbi.nlm.nih.gov/pubmed/32770075 http://dx.doi.org/10.1038/s41598-020-70220-w |