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Development and validation of a 1-year survival prognosis estimation model for Amyotrophic Lateral Sclerosis using manifold learning algorithm UMAP

Amyotrophic Lateral Sclerosis (ALS) is an inexorably progressive neurodegenerative condition with no effective disease modifying therapies. The development and validation of reliable prognostic models is a recognised research priority. We present a prognostic model for survival in ALS where result u...

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Detalles Bibliográficos
Autores principales: Grollemund, Vincent, Chat, Gaétan Le, Secchi-Buhour, Marie-Sonia, Delbot, François, Pradat-Peyre, Jean-François, Bede, Peter, Pradat, Pierre-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414917/
https://www.ncbi.nlm.nih.gov/pubmed/32770027
http://dx.doi.org/10.1038/s41598-020-70125-8