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Nanoparticle BAF312@CaP-NP Overcomes Sphingosine-1-Phosphate Receptor-1-Mediated Chemoresistance Through Inhibiting S1PR1/P-STAT3 Axis in Ovarian Carcinoma

PURPOSE: Platinum/paclitaxel-based chemotherapy is the strategy for ovarian cancer, but chemoresistance, inherent or acquired, occurs and hinders therapy. Therefore, further understanding of the mechanisms of drug resistance and adoption of novel therapeutic strategies are urgently needed. METHODS:...

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Detalles Bibliográficos
Autores principales: Gong, Ke, Dong, Yang, Wang, Liting, Duan, Yi, Yu, Jian, Sun, Ying, Bai, Min, Duan, Yourong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414939/
https://www.ncbi.nlm.nih.gov/pubmed/32801704
http://dx.doi.org/10.2147/IJN.S248667