Signaling via the p75 neurotrophin receptor facilitates amyloid-β-induced dendritic spine pathology

Synapse and dendritic spine loss induced by amyloid-β oligomers is one of the main hallmarks of the early phases of Alzheimer’s disease (AD) and is directly correlated with the cognitive decline typical of this pathology. The p75 neurotrophin receptor (p75(NTR)) binds amyloid-β oligomers in the nM r...

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Detalles Bibliográficos
Autores principales: Patnaik, Abhisarika, Zagrebelsky, Marta, Korte, Martin, Holz, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415136/
https://www.ncbi.nlm.nih.gov/pubmed/32770070
http://dx.doi.org/10.1038/s41598-020-70153-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415136/
https://www.ncbi.nlm.nih.gov/pubmed/32770070
http://dx.doi.org/10.1038/s41598-020-70153-4

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