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Signaling via the p75 neurotrophin receptor facilitates amyloid-β-induced dendritic spine pathology
Synapse and dendritic spine loss induced by amyloid-β oligomers is one of the main hallmarks of the early phases of Alzheimer’s disease (AD) and is directly correlated with the cognitive decline typical of this pathology. The p75 neurotrophin receptor (p75(NTR)) binds amyloid-β oligomers in the nM r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415136/ https://www.ncbi.nlm.nih.gov/pubmed/32770070 http://dx.doi.org/10.1038/s41598-020-70153-4 |