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Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab

In COVID-19, acute respiratory distress syndrome (ARDS) and thrombotic events are frequent, life-threatening complications. Autopsies commonly show arterial thrombosis and severe endothelial damage. Endothelial damage, which can play an early and central pathogenic role in ARDS and thrombosis, activ...

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Detalles Bibliográficos
Autores principales: Rambaldi, Alessandro, Gritti, Giuseppe, Micò, Maria Caterina, Frigeni, Marco, Borleri, Gianmaria, Salvi, Anna, Landi, Francesco, Pavoni, Chiara, Sonzogni, Aurelio, Gianatti, Andrea, Binda, Francesca, Fagiuoli, Stefano, Di Marco, Fabiano, Lorini, Luca, Remuzzi, Giuseppe, Whitaker, Steve, Demopulos, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier GmbH. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415163/
https://www.ncbi.nlm.nih.gov/pubmed/32943233
http://dx.doi.org/10.1016/j.imbio.2020.152001