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Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab
In COVID-19, acute respiratory distress syndrome (ARDS) and thrombotic events are frequent, life-threatening complications. Autopsies commonly show arterial thrombosis and severe endothelial damage. Endothelial damage, which can play an early and central pathogenic role in ARDS and thrombosis, activ...
Autores principales: | Rambaldi, Alessandro, Gritti, Giuseppe, Micò, Maria Caterina, Frigeni, Marco, Borleri, Gianmaria, Salvi, Anna, Landi, Francesco, Pavoni, Chiara, Sonzogni, Aurelio, Gianatti, Andrea, Binda, Francesca, Fagiuoli, Stefano, Di Marco, Fabiano, Lorini, Luca, Remuzzi, Giuseppe, Whitaker, Steve, Demopulos, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier GmbH.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415163/ https://www.ncbi.nlm.nih.gov/pubmed/32943233 http://dx.doi.org/10.1016/j.imbio.2020.152001 |
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