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miR‐322 treatment rescues cell apoptosis and neural tube defect formation through silencing NADPH oxidase 4

AIMS: Failure of neural tube closure resulting from excessive apoptosis leads to neural tube defects (NTDs). NADPH oxidase 4 (NOX4) is a critical mediator of cell growth and death, yet its role in NTDs has never been characterized. NOX4 is a potential target of miR‐322, and we have previously demons...

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Detalles Bibliográficos
Autores principales: Liu, Yu‐si, Gu, Hui, Huang, Tian‐chu, Wei, Xiao‐wei, Ma, Wei, Liu, Dan, He, Yi‐wen, Luo, Wen‐ting, Huang, Jie‐ting, Zhao, Duan, Jia, Shan‐shan, Wang, Fang, Zhang, Ting, Bai, Yu‐zuo, Wang, Wei‐lin, Yuan, Zheng‐wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415201/
https://www.ncbi.nlm.nih.gov/pubmed/32329577
http://dx.doi.org/10.1111/cns.13383