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miR‐322 treatment rescues cell apoptosis and neural tube defect formation through silencing NADPH oxidase 4
AIMS: Failure of neural tube closure resulting from excessive apoptosis leads to neural tube defects (NTDs). NADPH oxidase 4 (NOX4) is a critical mediator of cell growth and death, yet its role in NTDs has never been characterized. NOX4 is a potential target of miR‐322, and we have previously demons...
Autores principales: | Liu, Yu‐si, Gu, Hui, Huang, Tian‐chu, Wei, Xiao‐wei, Ma, Wei, Liu, Dan, He, Yi‐wen, Luo, Wen‐ting, Huang, Jie‐ting, Zhao, Duan, Jia, Shan‐shan, Wang, Fang, Zhang, Ting, Bai, Yu‐zuo, Wang, Wei‐lin, Yuan, Zheng‐wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415201/ https://www.ncbi.nlm.nih.gov/pubmed/32329577 http://dx.doi.org/10.1111/cns.13383 |
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