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Effect of intra‐ and inter‐tumoral heterogeneity on molecular characteristics of primary IDH‐wild type glioblastoma revealed by single‐cell analysis

AIMS: To reveal the effects of intra‐ and inter‐tumoral heterogeneity on characteristics of primary IDH‐wild type glioblastoma cells. METHODS: Single‐cell RNA‐seq data were acquired from the GEO database, and bulk sample transcriptome data were downloaded from the TCGA database with clinical informa...

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Detalles Bibliográficos
Autores principales: Xiong, Zujian, Yang, Qi, Li, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415209/
https://www.ncbi.nlm.nih.gov/pubmed/32488994
http://dx.doi.org/10.1111/cns.13396