Cargando…

Effect of intra‐ and inter‐tumoral heterogeneity on molecular characteristics of primary IDH‐wild type glioblastoma revealed by single‐cell analysis

AIMS: To reveal the effects of intra‐ and inter‐tumoral heterogeneity on characteristics of primary IDH‐wild type glioblastoma cells. METHODS: Single‐cell RNA‐seq data were acquired from the GEO database, and bulk sample transcriptome data were downloaded from the TCGA database with clinical informa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Zujian, Yang, Qi, Li, Xuejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415209/ https://www.ncbi.nlm.nih.gov/pubmed/32488994 http://dx.doi.org/10.1111/cns.13396

Ejemplares similares

Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma
por: Nam, Yoonhee, et al.
Publicado: (2023)

Molecular landscape of IDH ‐wild type, pTERT ‐wild type adult glioblastomas
por: Liu, Emma Munan, et al.
Publicado: (2022)

Hypoxia Contributes to Poor Prognosis in Primary IDH-wt GBM by Inducing Tumor Cells MES-Like Transformation Trend and Inhibiting Immune Cells Activity
por: Xiong, Zujian, et al.
Publicado: (2021)

Molecular profiling-based decision for targeted therapies in IDH wild-type glioblastoma
por: Kessler, Tobias, et al.
Publicado: (2020)

Transcriptional Characteristics of IDH-Wild Type Glioma Subgroups Highlight the Biological Processes Underlying Heterogeneity of IDH-Wild Type WHO Grade IV Gliomas
por: Chang, Yu-Zhou, et al.
Publicado: (2020)

Phosphorous Magnetic Resonance Spectroscopy and Molecular Markers in IDH1 Wild Type Glioblastoma
por: Galijašević, Malik, et al.
Publicado: (2021)

Isocitrate dehydrogenase 1 (IDH1) mutation-specific microRNA signature predicts favorable prognosis in glioblastoma patients with IDH1 wild type
por: Wang, Zheng, et al.
Publicado: (2013)

Improved Prognostic Prediction of Glioblastoma using a PAS Detected from Single-cell RNA-seq
por: Liu, Hongwei, et al.
Publicado: (2020)

Prognostic analysis and nomogram construction for older patients with IDH-wild-type glioblastoma
por: Cao, Wenjun, et al.
Publicado: (2023)

Mismatch repair protein mutations in isocitrate dehydrogenase (IDH)-mutant astrocytoma and IDH-wild-type glioblastoma
por: Richardson, Timothy E, et al.
Publicado: (2023)

GEN-10 WHOLE GENOME LANDSCAPE OF GLIOBLASTOMA, IDH-WILD TYPE
por: Nakashima, Takuma, et al.
Publicado: (2022)

Implications of Cellular Immaturity in Necrosis and Microvascularization in Glioblastomas IDH-Wild-Type
por: Orasanu, Cristian Ionut, et al.
Publicado: (2022)

HGG-56. EXTENSIVE MOLECULAR HETEROGENEITY WITHIN H3-/IDH-WILDTYPE PEDIATRIC GLIOBLASTOMA
por: Blattner-Johnson, Mirjam, et al.
Publicado: (2020)

Spatial progression and molecular heterogeneity of IDH-mutant glioblastoma determined by DNA methylation-based mapping
por: Lyon, James F., et al.
Publicado: (2021)

MYEF2: an immune infiltration-related prognostic factor in IDH-wild-type glioblastoma
por: Zhang, Yunxiao, et al.
Publicado: (2023)

Multiregional Sequencing of IDH-WT Glioblastoma Reveals High Genetic Heterogeneity and a Dynamic Evolutionary History
por: Franceschi, Sara, et al.
Publicado: (2021)

Association of plasma cell-free DNA with survival in patients with IDH wild-type glioblastoma
por: Bagley, Stephen J, et al.
Publicado: (2021)

Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma
por: Poon, Candice C., et al.
Publicado: (2019)

The Impact of Surgery in IDH 1 Wild Type Glioblastoma in Relation With the MGMT Deregulation
por: Marchi, Francesco, et al.
Publicado: (2020)

The Prognostic Value of NANO Scale Assessment in IDH-Wild-Type Glioblastoma Patients
por: Kasper, Johannes, et al.
Publicado: (2021)

Energy Metabolism in IDH1 Wild-Type and IDH1-Mutated Glioblastoma Stem Cells: A Novel Target for Therapy?
por: van Noorden, Cornelis J.F., et al.
Publicado: (2021)

Single-cell transcriptome analysis demonstrates inter-patient and intra-tumor heterogeneity in primary and metastatic lung adenocarcinoma
por: Liu, Yafei, et al.
Publicado: (2020)

Whole genome duplication is an early event leading to aneuploidy in IDH-wild type glioblastoma
por: Boisselier, Blandine, et al.
Publicado: (2018)

The Role of EGFR Amplification in Deep Venous Thrombosis Occurrence in IDH Wild-Type Glioblastoma
por: Kaye, Brandon, et al.
Publicado: (2023)

Increased RLIP76 expression in IDH1 wild-type glioblastoma multiforme is associated with worse prognosis
por: Wang, Qi, et al.
Publicado: (2020)

Tumor Heterogeneity and Molecular Characteristics of Glioblastoma Revealed by Single-Cell RNA-Seq Data Analysis
por: Yesudhas, Dhanusha, et al.
Publicado: (2022)

Updates in IDH-Wildtype Glioblastoma
por: Melhem, Jawad M., et al.
Publicado: (2022)

Association of hyperglycemia and molecular subclass on survival in IDH-wildtype glioblastoma
por: Liu, Elisa K, et al.
Publicado: (2022)

Inter- and intra-species heterogeneity in germination of Aspergillus conidia
por: Ijadpanahsaravi, Maryam, et al.
Publicado: (2022)

Diffusion tensor imaging‐based machine learning for IDH wild‐type glioblastoma stratification to reveal the biological underpinning of radiomic features
por: Wang, Zilong, et al.
Publicado: (2023)

MRI-Based Radiomics Combined with Deep Learning for Distinguishing IDH-Mutant WHO Grade 4 Astrocytomas from IDH-Wild-Type Glioblastomas
por: Hosseini, Seyyed Ali, et al.
Publicado: (2023)

Long noncoding RNA MALAT1 may be a prognostic biomarker in IDH1/2 wild-type primary glioblastomas
por: Argadal, Omer Gokay, et al.
Publicado: (2020)

Exome sequencing identifies frequent genomic loss of TET1 in IDH-wild-type glioblastoma()()
por: Stasik, Sebastian, et al.
Publicado: (2020)

Mutations and Copy Number Alterations in IDH Wild-Type Glioblastomas Are Shaped by Different Oncogenic Mechanisms
por: Ülgen, Ege, et al.
Publicado: (2020)

Prolonged response of recurrent IDH-wild-type glioblastoma to laser interstitial thermal therapy with pembrolizumab
por: Hwang, Helen, et al.
Publicado: (2022)

The Multifunctional Role of EMP3 in the Regulation of Membrane Receptors Associated with IDH-Wild-Type Glioblastoma
por: Martija, Antoni Andreu, et al.
Publicado: (2021)

Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH–Wild-Type Glioblastoma
por: Albert, Nathalie L., et al.
Publicado: (2023)

Integrated Analysis of the Clinical and Molecular Characteristics of IDH Wild-Type Gliomas in the Chinese Glioma Genome Atlas
por: Wang, Peng, et al.
Publicado: (2021)

Multi-dimensional omics characterization in glioblastoma identifies the purity-associated pattern and prognostic gene signatures
por: Xiong, Yi, et al.
Publicado: (2020)

Molecular classification of IDH-mutant glioblastomas based on gene expression profiles
por: Wu, Fan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2bhbldtplch5i5n3j1nll18iop