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Variable absorption of mutational trends by prion-forming domains during Saccharomycetes evolution
Prions are self-propagating alternative states of protein domains. They are linked to both diseases and functional protein roles in eukaryotes. Prion-forming domains in Saccharomyces cerevisiae are typically domains with high intrinsic protein disorder (i.e., that remain unfolded in the cell during...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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PeerJ Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415223/ https://www.ncbi.nlm.nih.gov/pubmed/32844065 http://dx.doi.org/10.7717/peerj.9669 |