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Variable absorption of mutational trends by prion-forming domains during Saccharomycetes evolution

Prions are self-propagating alternative states of protein domains. They are linked to both diseases and functional protein roles in eukaryotes. Prion-forming domains in Saccharomyces cerevisiae are typically domains with high intrinsic protein disorder (i.e., that remain unfolded in the cell during...

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Detalles Bibliográficos
Autor principal: Harrison, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415223/
https://www.ncbi.nlm.nih.gov/pubmed/32844065
http://dx.doi.org/10.7717/peerj.9669