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Bone marrow mesenchymal stem cells induce M2 microglia polarization through PDGF-AA/MANF signaling
BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) are capable of shifting the microglia/macrophages phenotype from M1 to M2, contributing to BMSCs-induced brain repair. However, the regulatory mechanism of BMSCs on microglia/macrophages after ischemic stroke is unclear. Recent evidence suggests...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415242/ https://www.ncbi.nlm.nih.gov/pubmed/32843919 http://dx.doi.org/10.4252/wjsc.v12.i7.633 |