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Bone marrow mesenchymal stem cells induce M2 microglia polarization through PDGF-AA/MANF signaling

BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) are capable of shifting the microglia/macrophages phenotype from M1 to M2, contributing to BMSCs-induced brain repair. However, the regulatory mechanism of BMSCs on microglia/macrophages after ischemic stroke is unclear. Recent evidence suggests...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Li, Wen-Bin, Qu, Ye-Wei, Gao, Jin-Xing, Tang, Yu-Shi, Wang, Dong-Jie, Pan, Yu-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415242/
https://www.ncbi.nlm.nih.gov/pubmed/32843919
http://dx.doi.org/10.4252/wjsc.v12.i7.633

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