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Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration

BACKGROUND: Glioblastoma (GBM) is a highly aggressive incurable brain tumor. The main cause of mortality in GBM patients is the invasive rim of cells migrating away from the main tumor mass and invading healthy parts of the brain. Although the motion is driven by forces, our current understanding of...

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Detalles Bibliográficos
Autores principales: Rezk, Rasha, Jia, Bill Zong, Wendler, Astrid, Dimov, Ivan, Watts, Colin, Markaki, Athina E, Franze, Kristian, Kabla, Alexandre J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415261/
https://www.ncbi.nlm.nih.gov/pubmed/32793884
http://dx.doi.org/10.1093/noajnl/vdaa081