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Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration
BACKGROUND: Glioblastoma (GBM) is a highly aggressive incurable brain tumor. The main cause of mortality in GBM patients is the invasive rim of cells migrating away from the main tumor mass and invading healthy parts of the brain. Although the motion is driven by forces, our current understanding of...
Autores principales: | Rezk, Rasha, Jia, Bill Zong, Wendler, Astrid, Dimov, Ivan, Watts, Colin, Markaki, Athina E, Franze, Kristian, Kabla, Alexandre J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415261/ https://www.ncbi.nlm.nih.gov/pubmed/32793884 http://dx.doi.org/10.1093/noajnl/vdaa081 |
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