Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype

PURPOSE: Wnt is a spatiotemporally regulated signaling pathway whose inhibition is associated with glaucoma, elevated intraocular pressure (IOP), and cell stiffening. Whether such changes are permanent or may be reversed is unclear. Here, we determine if activation of Wnt pathway after inhibition re...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhamodaran, Kamesh, Baidouri, Hasna, Sandoval, Lyndsey, Raghunathan, VijayKrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415288/
https://www.ncbi.nlm.nih.gov/pubmed/32539133
http://dx.doi.org/10.1167/iovs.61.6.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415288/
https://www.ncbi.nlm.nih.gov/pubmed/32539133
http://dx.doi.org/10.1167/iovs.61.6.30

Ejemplares similares