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Prostaglandin F2α Agonists Negatively Modulate the Size of 3D Organoids from Primary Human Orbital Fibroblasts

PURPOSE: To elucidate the molecular etiology of deepening of the upper eyelid sulcus (DUES) induced by prostaglandin (PG) analogs, a three-dimensional (3D) tissue culture system was employed using human orbital fibroblasts (HOFs). METHODS: During adipogenesis, changes in HOF 3D organoid sizes, as we...

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Detalles Bibliográficos
Autores principales: Itoh, Kaku, Hikage, Fumihito, Ida, Yosuke, Ohguro, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415291/
https://www.ncbi.nlm.nih.gov/pubmed/32503053
http://dx.doi.org/10.1167/iovs.61.6.13