VIP Induces Changes in the F-/G-Actin Ratio of Schlemm's Canal Endothelium via LRRK2 Transcriptional Regulation

PURPOSE: A previous study reported that vasoactive intestinal peptide (VIP) can regulate the cytoskeleton of Schlemm's canal (SC) endothelium and expand the SC lumen in a rat glaucoma model. In this study, we aimed to investigate the molecular mechanism of VIP on cytoskeleton regulation. METHOD...

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Detalles Bibliográficos
Autores principales: Yan, Xiaoqin, Li, Mu, Luo, Zhaoxia, Zhao, Yin, Zhang, Hong, Chen, Liwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415318/
https://www.ncbi.nlm.nih.gov/pubmed/32572455
http://dx.doi.org/10.1167/iovs.61.6.45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415318/
https://www.ncbi.nlm.nih.gov/pubmed/32572455
http://dx.doi.org/10.1167/iovs.61.6.45

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