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Inhibiting NF-κB Signaling Activation Reduces Retinal Neovascularization by Promoting a Polarization Shift in Macrophages

PURPOSE: Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling is involved in regulating tumor angiogenesis and metastasis; however, the exact mechanism of action in retinal neovascularization (RNV) remains unclear. The purpose of this study was to determine the role and u...

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Detalles Bibliográficos
Autores principales: Sui, Ailing, Chen, Xiuping, Demetriades, Anna M., Shen, Jikui, Cai, Yujuan, Yao, Yiyun, Yao, Yixuan, Zhu, Yanji, Shen, Xi, Xie, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415323/
https://www.ncbi.nlm.nih.gov/pubmed/32492108
http://dx.doi.org/10.1167/iovs.61.6.4