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Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in Diabetes
PURPOSE: Diabetic retinopathy (DR) is a leading cause of visual impairment. Müller cells in DR are dysfunctional due to downregulation of the inwardly rectifying potassium channel Kir4.1. Metformin, a commonly used oral antidiabetic drug, is known to elicit its action through 5′ adenosine monophosph...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415324/ https://www.ncbi.nlm.nih.gov/pubmed/32572457 http://dx.doi.org/10.1167/iovs.61.6.46 |