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Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes

Stroke is one of the leading causes of death worldwide. Accumulating evidence suggests that NLRP3 inflammasome activation plays an important role in ischemic stroke injury. However, the existence of the NLRP3 inflammasome in astrocytes remains controversial. In this study, we demonstrated the presen...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Chen, Manli, Lin, Kun, Xiang, Xuwu, Zheng, Yueying, Zhu, Shengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415396/
https://www.ncbi.nlm.nih.gov/pubmed/32788872
http://dx.doi.org/10.7150/ijms.44330