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Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells

The high recurrence rates of colorectal cancer have been associated with a small population of cancer stem cells (CSCs) that are resistant to the standard chemotherapeutic drug, 5-fluorouracil (5FU). Thymoquinone (TQ) has shown promising antitumor properties on numerous cancer systems both in vitro...

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Detalles Bibliográficos
Autores principales: Ballout, Farah, Monzer, Alissar, Fatfat, Maamoun, Ouweini, Hala El, Jaffa, Miran A., Abdel-Samad, Rana, Darwiche, Nadine, Abou-Kheir, Wassim, Gali-Muhtasib, Hala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415406/
https://www.ncbi.nlm.nih.gov/pubmed/32821342
http://dx.doi.org/10.18632/oncotarget.27426