NOX2 decoy peptides disrupt trauma-mediated neutrophil immunosuppression and protect against lethal peritonitis

Trauma and sepsis are frequent causes of immunosuppression and risk of secondary bacterial infections and mortality among critically ill patients. Reduced activity of neutrophil NADPH oxidase 2 (NOX2) and impaired bacterial killing are among the major indices of immunosuppression. We hypothesize tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Husain, Maroof, Becker, Eugene J., Bone, Nathaniel B., Schmitt, Amy, Pittet, Jean-Francois, Zmijewski, Jaroslaw W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415417/
https://www.ncbi.nlm.nih.gov/pubmed/32771683
http://dx.doi.org/10.1016/j.redox.2020.101651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415417/
https://www.ncbi.nlm.nih.gov/pubmed/32771683
http://dx.doi.org/10.1016/j.redox.2020.101651

Ejemplares similares