Discovery of Ebselen as an Inhibitor of 6PGD for Suppressing Tumor Growth

INTRODUCTION: The 6-phosphogluconate dehydrogenase (6PGD) was upregulated in many solid cancers and plays an important role in tumorigenesis. In the present study, we want to discover an old drug as an inhibitor of 6PGD for suppressing tumor growth. METHODS: We determined the expression of 6PGD in c...

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Detalles Bibliográficos
Autores principales: Feng, Qi, Li, Xiuru, Sun, Wenjing, Li, Yubo, Yuan, Yu, Guan, Baozhang, Zhang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415460/
https://www.ncbi.nlm.nih.gov/pubmed/32801914
http://dx.doi.org/10.2147/CMAR.S254853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415460/
https://www.ncbi.nlm.nih.gov/pubmed/32801914
http://dx.doi.org/10.2147/CMAR.S254853

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