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Fatty Acid Synthase (FASN) siRNA-Encapsulated-Her-2 Targeted Fab’-Immunoliposomes for Gene Silencing in Breast Cancer Cells

PURPOSE: The overexpression of Her-2 in 25–30% breast cancer cases and the crosstalk between Her-2 and fatty acid synthase (FASN) establishes Her-2 as a promising target for site-directed delivery. The present study aimed to develop the novel lipid base formulations to target and inhibit the cellula...

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Detalles Bibliográficos
Autores principales: Khan, Arif, Aljarbou, Ahmed N, Aldebasi, Yousef H, Allemailem, Khaled S, Alsahli, Mohammed A, Khan, Shamshir, Alruwetei, Abdulmohsen M, Khan, Masood A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415462/
https://www.ncbi.nlm.nih.gov/pubmed/32801705
http://dx.doi.org/10.2147/IJN.S256022