Monogenic and polygenic inheritance become instruments for clonal selection

Clonally expanded blood cells with somatic mutations (clonal hematopoiesis, CH) are commonly acquired with age and increase risk of blood cancer(1–9). The blood clones identified to date contain diverse large-scale mosaic chromosomal alterations (mCAs: deletions, duplications, and copy-neutral loss...

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Detalles Bibliográficos
Autores principales: Loh, Po-Ru, Genovese, Giulio, McCarroll, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415571/
https://www.ncbi.nlm.nih.gov/pubmed/32581363
http://dx.doi.org/10.1038/s41586-020-2430-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415571/
https://www.ncbi.nlm.nih.gov/pubmed/32581363
http://dx.doi.org/10.1038/s41586-020-2430-6

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