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Recurrent inversion toggling and great ape genome evolution

Inversions play an important role in disease and evolution but are difficult to characterize because their breakpoints map to large repeats. We increased by six-fold the number (n = 1,069) of previously reported great ape inversions using Strand-seq and long-read sequencing. We find that the X chrom...

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Detalles Bibliográficos
Autores principales: Porubsky, David, Sanders, Ashley D., Höps, Wolfram, Hsieh, PingHsun, Sulovari, Arvis, Li, Ruiyang, Mercuri, Ludovica, Sorensen, Melanie, Murali, Shwetha C., Gordon, David, Cantsilieris, Stuart, Pollen, Alex A., Ventura, Mario, Antonacci, Francesca, Marschall, Tobias, Korbel, Jan O., Eichler, Evan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415573/
https://www.ncbi.nlm.nih.gov/pubmed/32541924
http://dx.doi.org/10.1038/s41588-020-0646-x