Discovery of treatment for nerve agents targeting a new metabolic pathway

The inhibition of acetylcholinesterase is regarded as the primary toxic mechanism of action for chemical warfare agents. Recently, there have been numerous reports suggesting that metabolic processes could significantly contribute to toxicity. As such, we applied a multi-omics pipeline to generate a...

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Detalles Bibliográficos
Autores principales: Glaros, Trevor, Dhummakupt, Elizabeth S., Rizzo, Gabrielle M., McBride, Ethan, Carmany, Daniel O., Wright, Linnzi K. M., Forster, Jeffry S., Renner, Julie A., Moretz, Ruth W., Dorsey, Russell, Marten, Mark R., Huso, Walker, Doan, Alexander, Dorsey, Carrie D., Phillips, Christopher, Benton, Bernard, Mach, Phillip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415758/
https://www.ncbi.nlm.nih.gov/pubmed/32720192
http://dx.doi.org/10.1007/s00204-020-02820-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415758/
https://www.ncbi.nlm.nih.gov/pubmed/32720192
http://dx.doi.org/10.1007/s00204-020-02820-4

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