Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants

While the etiology of non-familial Parkinson’s disease (PD) remains unclear, there is evidence that increased levels of tissue iron may be a contributing factor. Moreover, exposure to some environmental toxicants is considered an additional risk factor. Therefore, brain-targeted iron chelators are o...

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Detalles Bibliográficos
Autores principales: Gutbier, Simon, Kyriakou, Sotiris, Schildknecht, Stefan, Ückert, Anna-Katharina, Brüll, Markus, Lewis, Frank, Dickens, David, Pearson, Liam, Elson, Joanna L., Michel, Sylvia, Hubscher-Bruder, Véronique, Brandel, Jeremy, Tetard, David, Leist, Marcel, Pienaar, Ilse S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415766/
https://www.ncbi.nlm.nih.gov/pubmed/32607613
http://dx.doi.org/10.1007/s00204-020-02826-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415766/
https://www.ncbi.nlm.nih.gov/pubmed/32607613
http://dx.doi.org/10.1007/s00204-020-02826-y

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