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Nephrotic syndrome‐associated hypercoagulopathy is alleviated by both pioglitazone and glucocorticoid which target two different nuclear receptors

BACKGROUND: Thrombosis is a potentially life‐threatening nephrotic syndrome (NS) complication. We have previously demonstrated that hypercoagulopathy is proportional to NS severity in rat models and that pioglitazone (Pio) reduces proteinuria both independently and in combination with methylpredniso...

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Detalles Bibliográficos
Autores principales: Waller, Amanda P., Agrawal, Shipra, Wolfgang, Katelyn J., Kino, Jiro, Chanley, Melinda A., Smoyer, William E., Kerlin, Bryce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415912/
https://www.ncbi.nlm.nih.gov/pubmed/32776495
http://dx.doi.org/10.14814/phy2.14515