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Octyl gallate induces hepatic steatosis in HepG2 cells through the regulation of SREBP-1c and PPAR-gamma gene expression

Octyl gallate (OG) is an antioxidant commonly used in food, although there is no definition of its acceptable daily intake. There are reports in vitro and in vivo showing that food additives and drugs can alter lipid metabolism. Lipid droplet accumulation in hepatic cells is one of the main findings...

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Detalles Bibliográficos
Autores principales: Lima, Kelly Goulart, Schneider Levorse, Vitor Giancarlo, Rosa Garcia, Maria Claudia, de Souza Basso, Bruno, Pasqualotto Costa, Bruna, Antunes, Gessica Luana, Luft, Carolina, Haute, Gabriela Viegas, Leal Xavier, Léder, Donadio, Márcio Vinícius Fagundes, Rodrigues de Oliveira, Jarbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415935/
https://www.ncbi.nlm.nih.gov/pubmed/32788910
http://dx.doi.org/10.17179/excli2020-2214