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Octyl gallate induces hepatic steatosis in HepG2 cells through the regulation of SREBP-1c and PPAR-gamma gene expression
Octyl gallate (OG) is an antioxidant commonly used in food, although there is no definition of its acceptable daily intake. There are reports in vitro and in vivo showing that food additives and drugs can alter lipid metabolism. Lipid droplet accumulation in hepatic cells is one of the main findings...
Autores principales: | Lima, Kelly Goulart, Schneider Levorse, Vitor Giancarlo, Rosa Garcia, Maria Claudia, de Souza Basso, Bruno, Pasqualotto Costa, Bruna, Antunes, Gessica Luana, Luft, Carolina, Haute, Gabriela Viegas, Leal Xavier, Léder, Donadio, Márcio Vinícius Fagundes, Rodrigues de Oliveira, Jarbas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415935/ https://www.ncbi.nlm.nih.gov/pubmed/32788910 http://dx.doi.org/10.17179/excli2020-2214 |
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