Cargando…

In vitro metabolic profile and drug‐drug interaction assessment of secnidazole, a high‐dose 5‐nitroimidazole antibiotic for the treatment of bacterial vaginosis

A single‐dose oral granule formulation of secnidazole 2 g (SOLOSEC(™)) has been approved in the US as a treatment for bacterial vaginosis. Available data on the likelihood of in vitro drug‐drug and alcohol‐drug interactions are limited. Secnidazole was incubated with cultured human hepatocytes over...

Descripción completa

Detalles Bibliográficos
Autores principales: Pentikis, Helen S., Adetoro, Nikki, Kaufman, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416039/
https://www.ncbi.nlm.nih.gov/pubmed/32776491
http://dx.doi.org/10.1002/prp2.634